Authors
Marília Brito Gomes, Fernanda Oliveira Braga de Albuquerque, Alessandra Matheus, Luiz Henrique Canani, Adriana Costa Forti, Reine Marie Chaves, Elizabeth João Pavin, Renan Montenegro Junior, Sergio A Dib, João S Felicio, Rosangela Roginski Réa, Marcia Nery, Carlos Antonio Negrato, Luana Casari Silva
Published in
Clinics (Sao Paulo, Brazil). Volume 81. Pages 101082. Sep 13, 2026. Epub Sep 13, 2026.
Abstract
To assess the 5- and 10-year Cardiovascular Disease (CVD) risk among Brazilian patients with Type 1 Diabetes (T1D) using the Steno Type 1 Risk Engine (ST1RE), and to evaluate the prevalence of clinical CVD, analyzing traditional and non-traditional risk factors.
This was a cross-sectional multicenter study conducted in 13 public clinics in 11 Brazilian cities, involving 1,760 patients. The ST1RE was used in patients without previous CVD (n = 1,300).
The prevalence of CVD was 2.1%, with ischemic heart disease being the most common. These patients were older, had higher age at T1D diagnosis, and longer diabetes duration when CVD was diagnosed. According to ST1RE 10-year risk, 70.7% were classified as low, 18.0% as moderate, and 11.3% as high risk without differences regarding sex. A lower use of cardioprotective drugs was noted in patients with moderate/high 10-year ST1RE in relation to guidelines recommendations. Higher age at diagnosis, presence of retinopathy, elevated high-sensitivity C-reactive protein, and uric acid levels were associated to moderate/high ST1RE risk.
Almost 30% of our patients had moderate/high ST1RE risk and were undertreated for CVD risk factors. This highlights the need to establish strategies to improve cardiovascular and diabetes management risk in routine clinical practice.
PMID:
42732703
Bibliographic data and abstract were imported from PubMed on 14 Sep 2026.
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