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Cholesterol embolization syndrome: A case report and literature review.

Created on 14 Sep 2026

Authors

Xiaojie Zhang

Published in

Journal of vascular surgery cases and innovative techniques. Volume 12. Issue 6. Pages 102422. Epub Jul 22, 2026.

Abstract

Cholesterol embolization syndrome is a clinical condition caused by cholesterol crystals dislodged from atherosclerotic plaques, leading to distal arterial occlusion and subsequent organ ischemia. We present a case of a 61-year-old male who developed blue toe syndrome, reticular livedo, and gastrointestinal bleeding 1 week after aortic interventional therapy for intermittent claudication. The patient exhibited eosinophilia and multiorgan dysfunction. Diagnosis was confirmed by fundoscopic examination revealing a cherry-red spot at the macula. This case, combined with a literature review, discusses the clinical features, diagnostic criteria, and therapeutic strategies of this disease to enhance clinician awareness. The patient was followed for 3 months with ongoing follow-up thereafter, during which renal function partially recovered from stage 4 to stage 3b chronic kidney disease with conservative management.

PMID:
42733541
Bibliographic data and abstract were imported from PubMed on 14 Sep 2026.

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