Renal Drug Dosing and Medication Safety in Patients Receiving Dialysis: A Practical Guide for Nephrology Nurses and Advanced Practice Providers.

Authors

Leah Foster Smith

Published in

Nephrology nursing journal : journal of the American Nephrology Nurses' Association. Volume 53. Issue 4. Pages 301-348.

Abstract

Patients receiving dialysis are among the most medically complex populations in health care and are at high risk for medication-related problems. Polypharmacy, frequent hospitalizations, multiple comorbid conditions, and care from numerous health care providers contribute to medication discrepancies and adverse drug events. In addition, advanced kidney disease significantly alters drug absorption, distribution, metabolism, and elimination, requiring careful application of renal drug dosing principles. Nephrology nurses and advanced practice providers play critical roles in medication reconciliation, patient education, monitoring for adverse effects, and promoting medication safety. This article reviews dialysis pharmacokinetics, principles of renal drug dosing, common medication considerations in patients on dialysis, and practical strategies to optimize medication safety and therapeutic outcomes.

PMID:
42742302
Bibliographic data and abstract were imported from PubMed on 15 Sep 2026.

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