Enzyme evolution and metabolic engineering for 5-aminolevulinic acid production.

Authors

Sefli Sri Wahyu Effendi, Yu-Chieh Lin, I-Son Ng

Published in

Trends in biotechnology. Sep 15, 2026. Epub Sep 15, 2026.

Abstract

5-Aminolevulinic acid (5-ALA), a nonproteinogenic amino acid, has emerged as a versatile metabolite for applications in health, agriculture, and sustainability. Advances in ALA synthase engineering and metabolic rewiring have enabled scalable biosynthesis. The next frontier should expand beyond production, positioning it as a gateway to future biotechnological applications.

PMID:
42744682
Bibliographic data and abstract were imported from PubMed on 16 Sep 2026.

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