Authors
Shicheng Li, Yubao Hu, Jie Shen, Mengjie Wang, Yucheng Zhong
Published in
JACC. Case reports. Pages 110331. Sep 16, 2026. Epub Sep 16, 2026.
Abstract
Cor triatriatum sinistrum (CTS) is a rare congenital malformation, and its coexistence with degenerative mitral regurgitation (MR) in older adults is exceptionally rare and creates substantial technical challenges for transcatheter interventions.
We report a 78-year-old woman presenting with progressive dyspnea, palpitations, and lower limb edema secondary to severe MR caused by posterior mitral leaflet prolapse. Preprocedural imaging incidentally identified a complete, nonfenestrated CTS membrane. Three clips were sequentially implanted at the prolapse site, downgrading MR from severe to trace. The final mean transmitral gradient was 3 mm Hg. The patient achieved rapid symptom resolution and was discharged 7 days postprocedure.
This case establishes the feasibility of mitral transcatheter edge-to-edge repair in patients with CTS through meticulous preprocedural planning and controlled transmembranous access. It broadens the therapeutic landscape for anatomically complex, surgically prohibitive older adults with valvular disease.
The mitral transcatheter edge-to-edge repair is feasible and safe in MR with CTS.
PMID:
42747362
Bibliographic data and abstract were imported from PubMed on 16 Sep 2026.
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