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Pharmacological lipid-lowering therapies for primary and secondary prevention of cardiovascular disease in adults with dyslipidaemia: a systematic review and network meta-analysis.

Created on 16 Sep 2026

Authors

Kamyar Shokraee, Brenda Bongaerts, Petek Eylul Taneri, Camila Micaela Escobar Liquitay, Siavosh Olfati, Ana-Mihaela Zorger, Nicole Skoetz, Juan Va Franco

Published in

The Cochrane database of systematic reviews. Volume 9. Pages CD016387. Sep 16, 2026. Epub Sep 16, 2026.

Abstract

This is a protocol for a Cochrane review (intervention). The objectives are as follows: Primary To compare the effects and safety of lipid-lowering therapies, including statin regimens (high intensity, moderate intensity, and low intensity), non-statin therapies, and combination regimens, for the primary and secondary prevention of cardiovascular disease in adults, using pairwise and network meta-analysis where appropriate. Secondary To obtain an estimate of the relative ranking of these lipid-lowering therapies compared to placebo/no treatment.

PMID:
42746925
Bibliographic data and abstract were imported from PubMed on 16 Sep 2026.

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