[Prostate-Preserving Curative Surgery for Isolated Peritoneal Recurrence with Seminal Vesicle Invasion Following Sigmoid Colon Cancer Resection-A Case Report].

Authors

Fuka Fujimoto, Shigeyuki Kosaka, Naoi Sato, Haruka Shigemori, Haruka Kirihara, Ryo Nakajima, Shinnosuke Harata, Kawori Watanabe, Tomoya Shamoto, Kazuyoshi Shiga, Tatsuya Tanaka, Yoichi Matsuo, Shuji Takiguchi

Published in

Gan to kagaku ryoho. Cancer & chemotherapy. Volume 53. Issue 9. Pages 595-597.

Abstract

A 61-year-old man presented with bowel obstruction caused by sigmoid colon cancer that was detected during screening. After colonic stenting, laparoscopic sigmoidectomy was performed (pT3N0M0, Stage Ⅱa). Follow-up CT performed 2 years later revealed a nodular lesion anterior to the rectum. MRI and PET-CT confirmed peritoneal recurrence invading the rectum and bilateral seminal vesicles. Neoadjuvant chemotherapy comprising 5 courses of mFOLFOX6 plus bevacizumab reduced the tumor size from 19 × 12 mm to 11 × 7 mm. Although total pelvic exenteration was initially considered, tumor shrinkage ultimately enabled prostate preservation. Robot-assisted laparoscopic low anterior resection with bilateral seminal vesicle resection and a diverting stoma was performed. The patient's postoperative course was uneventful, allowing discharge on postoperative day 10. Pathological examination confirmed negative margins, indicating curative resection. This case suggests that chemotherapy-induced tumor shrinkage may facilitate organ-preserving surgery in patients with advanced recurrent colorectal cancer.

PMID:
42750628
Bibliographic data and abstract were imported from PubMed on 17 Sep 2026.

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