Authors
Francisco José Pelegrín-Mateo, Álvaro Muñoz Abad, Beatriz Grau Mirete, Mariano Martínez Marín, Cristina Bernabé Martínez, Elena Navarro Vicente, María Orengo López, Marta Hernández Sáez, Jose María Barón Saura, Elena Asensio Martínez, Javier Gallego Plazas
Published in
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. Sep 17, 2026. Epub Sep 17, 2026.
Abstract
Social determinants of health (SDOH) may influence cancer outcomes, although their integration in routine clinical records remains limited.
This retrospective two-center cohort included adults with histologically confirmed advanced colorectal adenocarcinoma diagnosed in 2023. Clinical variables and prespecified SDOH were extracted from electronic medical records. The primary endpoint was documentation completeness for each SDOH variable.
Forty-four patients were included. Clinical variables were consistently documented, whereas SDOH showed substantial missing data. Missingness was moderate for type of residence (20.5%), cohabitation (27.3%), caregiving support (27.3%), and marital status (29.5%), but high for social isolation (88.6%), education (95.5%), chronic stress (97.7%), and perceived job-loss risk (97.7%). Mean missing SDOH data per patient was 48.3% (± 22).
Routine oncology records capture clinical data more consistently than SDOH. These findings provide rationale for the prospective GEO-CRC phase focused on standardized SDOH collection and outcome evaluation.
PMID:
42753075
Bibliographic data and abstract were imported from PubMed on 18 Sep 2026.
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