Authors
Chenxi Huang, Sanyi Tang, Qianqian Zhang
Published in
Journal of biological dynamics. Volume 20. Issue 1. Pages 2732280. Dec 31, 2026. Epub Sep 18, 2026.
Abstract
This paper establishes a state-feedback control system based on a nonlinear incidence SIRS model to explore the regulatory mechanism of infectious disease control. We develop a state-dependent impulsive model with threshold-triggered vaccination and isolation interventions once the susceptible population exceeds a predefined level. After investigating the basic properties of the ODE subsystem, we define and classify the Poincaré map and analyze its domain, range and monotonicity, which provides a theoretical basis for studying positive periodic solutions of the impulsive system under different ODE dynamics. The results show that the disease-free periodic solution is globally asymptotically stable for , where is a parameter directly related to the force of the infection. When , however, the model may exhibit bistability between the disease-free periodic solution and an endemic periodic solution, where the final outcome depends sensitively on the initial infection size, which is consistent with the weak transmissibility and controllable low-level prevalence.
PMID:
42757765
Bibliographic data and abstract were imported from PubMed on 18 Sep 2026.
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