Authors
Tae Wan Park, Haohui Zhang, Chanho Park, Seth D Goldstein, Lindsey Wade, Eric Rytkin, Alicia J McLuckie, Yalcin Kulahci, Ramu Janarthanan, Tae Yeon Kim, Min-Seung Jo, Bedreddin Sazoglu, Zeynep Demir, Omer Dirican, Fatma Esra Demir, Woo-Youl Maeng, Seonggwang Yoo, Peter Saba, Kaiqing Zhang, Hak-Young Ahn, Jong Uk Kim, Jamin Lee, Anthony Banks, Seyong Oh, Kyeongha Kwon, Alan Nugent, Igor R Efimov, Vijay S Gorantla, Andrew Pelech, Yonggang Huang, John A Rogers
Published in
Science advances. Volume 12. Issue 38. Pages eaeg8187. Sep 18, 2026. Epub Sep 18, 2026.
Abstract
In vivo fluorescence signals provide physiological and pathological insights for the interpretation of biological states associated with anatomical abnormalities or disease. Conventional methods for measuring fluorescence signals rely on bulky, costly instrumentation for imaging or for localized sensing. Here, we report a compact, wireless fluorimeter system for continuous, real-time measurements of the dynamics of fluorescence signals at locations of interest across the body. The approach represents a type of wearable that enables quantitative, interpretable fluorescence readouts and automatic data streaming to standard smart devices. The platform is compatible with injectable fluorescent species of medical relevance, such as indocyanine green, fluorescein, and methylene blue. Measurements from ischemic rodent and healthy porcine models, as well as those associated with limb amputation/replantation studies in rodents, demonstrate physiologically meaningful fluorescence profiles, with validation against ex situ blood analysis. These conceptual and technical advances offer the potential for convenient, continuous monitoring of fluorescence signals to support disease management and long-term patient care.
PMID:
42758847
Bibliographic data and abstract were imported from PubMed on 19 Sep 2026.
Read full publication at:
Please sign in
to see all details.
Advertisement
Stats
- Recommendations n/a n/a positive of 0 vote(s)
- Views 9
- Comments 0