Ten-Year Outcomes of Early Suboptimal Graft Function Following Deceased Donor Kidney Transplantation.

Authors

Sangkyun Mok, Sang Seob Yun, Sun Cheol Park, Eun Ju Jang, Young Jun Park, Kang Woong Jun, Ji Il Kim, Jeong Kye Hwang, Hyung Jin Cho, Mi Hyeong Kim

Published in

Transplantation proceedings. Sep 18, 2026. Epub Sep 18, 2026.

Abstract

Early graft function is a critical predictor of long-term outcomes in kidney transplantation. This study evaluated 10-year outcomes in patients with suboptimal graft function (SGF) during the first month after deceased donor kidney transplantation (DDKT).
In this retrospective study of 294 adult DDKT recipients (February 2006-January 2014), SGF was defined as the lowest serum creatinine >1.5 mg/dL during the first month. Cases with a creatinine ≤1.5 mg/dL were categorized as the standard outcome group. Primary outcomes were 10-year graft and patient survival.
Suboptimal graft function was associated with significantly poorer long-term graft survival (5-year: 82.3% vs 92.7%; 10-year: 63.2% vs 89.1%). Overall mortality did not differ between groups. Delayed graft function alone showed no significant association with graft survival. Donor age ≥ 60 years was also associated with inferior graft survival.
Suboptimal early creatinine elevation is a significant predictor of long-term graft outcomes. Donor age is an important determinant of long-term graft outcomes.

PMID:
42760215
Bibliographic data and abstract were imported from PubMed on 19 Sep 2026.

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