Expanding Horizons in Fertility Preservation: Diverse Populations, Emerging Indications, and Ethical Considerations.

Authors

Allison Eubanks, Eric Widra

Published in

Fertility and sterility. Sep 21, 2026. Epub Sep 21, 2026.

Abstract

Fertility preservation has traditionally centered on intervention before gonadotoxic cancer treatment, yet many patients do not fit this conventional pathway. Reproductive risk may arise before puberty, result from a genetic predisposition to primary ovarian insufficiency, intersect with gender-affirming care, or be recognized only after gonadotoxic exposure. This Views and Reviews series examines fertility preservation in transgender and gender-diverse patients, girls before and during puberty, patients with genetic conditions associated with primary ovarian insufficiency, and individuals seeking preservation after chemotherapy or radiation. Across these settings, evidence is frequently limited, the optimal timing of intervention may be uncertain, and technical feasibility does not necessarily predict future reproductive benefit. The series considers clinical strategies and outcomes alongside access, procedural burden, autonomy, psychosocial effects, and long-term safety, providing a framework for individualized counseling as fertility-preservation indications continue to evolve.

PMID:
42767397
Bibliographic data and abstract were imported from PubMed on 22 Sep 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.