Ancient mechanics: Bacterial MAIN domains reveal an evolutionary link to eukaryotic mechanotransduction.

Authors

Kumaran S Ramamurthi

Published in

Current biology : CB. Volume 36. Issue 18. Pages R979-R982. Sep 21, 2026.

Abstract

A newly discovered family of microbial autoproteolytic domains suggests that bacteria and animals may share a common strategy for responding to physical forces. Beyond uncovering an ancient protein fold, this work opens new questions about how microbes use mechanical cues to regulate adhesion, nutrient acquisition, virulence, and surface interactions.

PMID:
42767199
Bibliographic data and abstract were imported from PubMed on 22 Sep 2026.

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