Recent Advances in Synthetic Strategies and Agrochemical Activities of Isoxazoline Derivatives.

Authors

Yang-Xi He, Wang-Xiang Li, De-Shuang Zhang, Yan-Qing Gao, Peng Lei

Published in

Current organic synthesis. Volume 23. Issue 3. Pages 159-173.

Abstract

Isoxazoline derivatives have garnered significant attention in recent years due to their versatile chemical structures and broad-spectrum biological activities, and various isoxazoline derivatives have been explored as promising fungicides, insecticides, and herbicides. The exploration of isoxazoline derivatives has become a focal point in pesticide research. Based on findings of different researchers working on synthesis and agrochemical activity evaluation of isoxazoline derivatives, this review will comprehensively summarize the recent advances on the synthetic strategies such as cycloaddition and asymmetric dearomatization, as well as the antifungal, insecticidal, and herbicidal activities of isoxazoline derivatives over the past five years. The future development perspectives of isoxazoline derivatives as environmentally friendly agrochemicals will be provided. This review aims to offer a comprehensive understanding of the application potential of isoxazoline derivatives in modern agriculture and to inspire further research in this field, and we believe the continuous exploration and development of isoxazoline derivatives will be expected to make significant contributions to the advancement of innovative and eco-friendly agrochemicals.

PMID:
42768498
Bibliographic data and abstract were imported from PubMed on 22 Sep 2026.

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