Authors
Jiawen Tian, Wei Yang, Wenting Cui, Shuran Wu, Dan Zhou, Minyan Hu, Fangwei Zhao, Jixiang Hu, Yueqi Wang, Bengt Lindholm, Longkai Li, Hongli Lin
Published in
Renal failure. Volume 48. Issue 1. Pages 2730668. Epub Sep 21, 2026.
Abstract
A refractory catheter-related infection in patients receiving peritoneal dialysis (PD) represents a major challenge that may require catheter removal and reinsertion. We assessed the effect of a tunnel reconstruction operation on refractory infection in a single center.
We retrospectively collected data from 10 PD patients who, after inadequate responses to treatment with culture-based antibiotic therapy, underwent a tunnel reconstruction operation designed to resolve a refractory catheter-related infection without requiring transition to hemodialysis. The patients were followed for 3-41 months, and outcomes at months 3 and 12 were analyzed.
Tunnel reconstruction surgery was performed in 10 patients, including 7 with exit-site infection and 3 with tunnel infection. No patients developed catheter-related infection, catheter dysfunction, or postoperative complications after 3 months of postoperative follow-up. During the 12-month postoperative follow-up period, there were no catheter-related infections among 7 patients (3 patients were not followed for 12 months). However, 2 patients developed an exit-site infection episode at 33 and 41 months after tunnel reconstruction surgery, respectively. No incidents of PD connector hypersensitivity or catheter leakage occurred during the follow-up period.
Tunnel reconstruction operation may be a promising salvage option that requires prospective validation in PD patients with refractory catheter-related infections.
PMID:
42768893
Bibliographic data and abstract were imported from PubMed on 22 Sep 2026.
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