Psychometric Properties of the EORTC QLQ-LC29 Module for Assessing Quality of Life in Patients with Lung Cancer: An Observational Study in Antioquia, Colombia.

Authors

Miguel Angel Medina-Pabón, Jose F Tatis-Méndez, Yeimys E Pérez-García, Héctor I García-García, Michael Koller

Published in

International journal of psychological research. Volume 19. Issue 1. Pages 15-23. Epub Jun 12, 2026.

Abstract

The purpose of this study is to evaluate the psychometric properties of the Spain Spanish version of the European Organisation for Research and Treatment of Cancer - Quality of Life Questionnaire - Lung Cancer Module-29 (EORTC QLQ-LC29) in Colombia.
Content validity was assessed with confirmatory factor analysis, concurrent criterion validity by comparing scores of the QLQ-LC29 and Functional Assessment of Cancer Therapy - Lung (FACT-L) scales, internal consistency by Cronbach's alpha, test-retest reliability with Lin's concordance coefficient, and sensitivity to change after therapeutic intervention by comparing averages in repeated measurements.
The EORTC QLQ-LC29 was administered to 292 patients aged 19 to 92 years with a diagnosis of lung cancer. Factor analysis showed acceptable model fit. In the concurrent validity assessment, a significant moderate negative correlation was found between the QLQ-LC29 domains of cough symptoms (-0.499), dyspnea (-0.468), and well-being in the FACT-L module. A moderate negative correlation was also found between fear of disease progression (-0.554) and emotional well-being on the FACT-L scale; Cronbach's alpha of the overall scale was 0.81; Lin's coefficient was between 0.54 and 0.98; differences between scores before and after a therapeutic intervention were significant only for the domain "Side effects of treatment".
Cultural adaptation of the Spain version of the EORTC QLQ-LC29 was necessary to ensure its internal consistency, stability, feasibility, content validity, criterion validity, and construct validity for measuring quality of life in Colombian lung cancer patients.

PMID:
42773996
Bibliographic data and abstract were imported from PubMed on 23 Sep 2026.

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