Parvamide A, one previously undescribed lignan amide from Glycosmis parviflora kurz.

Authors

Jin-Er Cai, Meng-Jie Chen, Tan-Yu Chen, Jing-Wen Mo, Xiao-Li Luo, Jing-Ling Ren, Pei-Lian Liu, Wu Zhang, Hong-Yan Yang, Zhong-Liu Zhou, Zi-Ming Chen, Hua-Lin Zhang, Qing Yan, Shou-Yuan Wu

Published in

Natural product research. Pages 1-8. Sep 23, 2026. Epub Sep 23, 2026.

Abstract

To discover bioactive metabolites from medicinal plants, the ethyl acetate extract from Glycosmis parviflora leaves was subjected to phytochemical analysis. A total of seven compounds were purified and structurally characterised, including one previously undescribed lignan amide, parvamide A, alongside six known sulphonyl amides (2-7). The structure of compound (1) was determined by extensive spectroscopy methods, including 1D and 2D-NMR, HRESIMS, IR, UV, DP4+ probability analysis and calculated ECD. Furthermore, all compounds (1-7) were evaluated for antibacterial activities in vitro.

PMID:
42777238
Bibliographic data and abstract were imported from PubMed on 24 Sep 2026.

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