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Needle-Induced HU Bias Correction for Quantitative CT Thermometry in CT-Guided Microwave Ablation: An Ex Vivo Feasibility Study.

Created on 24 Sep 2026

Authors

Tiansheng Liu, Jihong Chen, Xiaolong Wang, Jie Chen, Zhuting Fang, Bingwei He

Published in

Academic radiology. Sep 23, 2026. Epub Sep 23, 2026.

Abstract

Metallic microwave ablation antennas introduce structured Hounsfield unit (HU) bias that can degrade quantitative CT thermometry. We developed a needle-centered method to suppress its repeatable low-frequency component.
This ex vivo feasibility study used six porcine liver specimens. Three livers provided independent room-temperature HU-temperature calibration, yielding κ=-0.31°C/HU. HU was measured as the mean within a 2-mm-diameter circular ROI centered at the temperature-probe tip. E1 used two no-antenna repeat scans; E2 used three scans at each of two antenna orientations; E5 acquired three scans at each of three orientations, with one representative matched comparison per orientation used for the orientation-specific AAI and low-frequency suppression analysis. E4 comprised two spatially separated, independent 50-W ablation runs in the same liver, evaluated at 3 and 5 min, with nine predefined locations per run. Each run used its own pre-heating baseline and correction profile.
Antenna placement produced a repeatable structured HU-bias component beyond baseline variability. Correction reduced large- and mid-scale low-frequency energy by 77.36% and 71.69%, respectively. Across all nine E4 locations, median absolute temperature error decreased from 6.8°C to 6.1°C at 3 min and from 7.1°C to 5.9°C at 5 min. At the three corrected near-antenna locations, median absolute error decreased from 6.8°C to 2.2°C and from 7.1°C to 2.0°C, respectively.
Needle-centered HU-bias correction improved CT thermometry in controlled ex vivo ablation, particularly at near-antenna locations with measurable bias.

PMID:
42778472
Bibliographic data and abstract were imported from PubMed on 24 Sep 2026.

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