Aphasic Status Epilepticus as a Stroke Mimic: A Literature Review.

Authors

Yuichiro Inatomi, Makoto Nakajima, Toshiro Yonehara

Published in

Internal medicine (Tokyo, Japan). Sep 22, 2026. Epub Sep 22, 2026.

Abstract

We reviewed the clinical features of previously reported cases of aphasic status epilepticus. In an analysis of medical information from 87 reported cases (92 attacks), the types of aphasia associated with aphasic status epilepticus were global aphasia in 44 (48%) of 92 attacks, motor aphasia in 29 (32%), and sensory aphasia in 11 (12%) attacks. The findings of diffusion and perfusion imaging, as well as electroencephalography, were often compatible with aphasia, although variations in the distribution and findings were observed in several cases. Furthermore, in 16 (32%) of 67 attacks, it took more than 1 week from the onset of the aphasic status epilepticus to treatment; therefore, the sequelae of aphasia were observed in 18 (20%) of 92 attacks. Aphasic status epilepticus should be considered a stroke mimic and it may cause sequelae due to delayed treatment. Patients suspected of having aphasic status epilepticus should be immediately treated with benzodiazepine without waiting for either electroencephalography or perfusion imaging.

PMID:
42778382
Bibliographic data and abstract were imported from PubMed on 24 Sep 2026.

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