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Prebiotics in Food Fermentation and Bioprocessing: Advances and Applications.

Created on 25 Sep 2026

Authors

Sasmita Dash, Sonali Dutta, Priyanka Dash, Jitu Halder, Chandan Das, Goutam Ghosh, Goutam Rath, Biswakanth Kar

Published in

Current pharmaceutical biotechnology. Sep 22, 2026. Epub Sep 22, 2026.

Abstract

Prebiotics are nondigestible food components that selectively stimulate beneficial gut microbiota and have garnered significant attention in food science and biotechnology because of their health-promoting properties. Among them, fructooligosaccharides and galactooligosaccharides are especially important for their positive effects on human health. Functional foods with enhanced nutritional and medicinal value have been made possible by the recent use of prebiotics in food fermentation and bioprocessing. This review summarizes recent developments in prebiotic production and application, with emphasis on biotechnological approaches such as microbial fermentation, enzymatic synthesis, and strain improvement techniques, based on literature retrieved from PubMed, Scopus, and Web of Science up to July 2025. Advances in fermentation technologies, including solid-state fermentation and co-culture systems, are also discussed for optimizing production processes. In addition, the review highlights the health-promoting effects of prebiotics, including modulation of gut microbiota, immunological regulation, and involvement in the gut-brain axis. Lastly, we highlighted current challenges and prospects, emphasizing their application to transform fermented foods and bioprocessing techniques.

PMID:
42786825
Bibliographic data and abstract were imported from PubMed on 25 Sep 2026.

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