Authors
Ziv Lautman, Lila Gravellier, Shaista Malik, Michael Hittle, Francois Haddad, Helge Ræder, Michael P Snyder
Published in
JACC. Case reports. Pages 110397. Sep 25, 2026. Epub Sep 25, 2026.
Abstract
Consumer wearables provide continual physiological data, including multiple cardiovascular metrics, yet their use in detecting physiological changes that precede cardiac events remains limited.
A 76-year-old man with structural heart disease experienced sudden cardiac death minutes after high-intensity indoor cycling. Change-point analysis of wearable-captured physiology revealed a coordinated step-change, with most changes clustering 4-6 months before the sudden cardiac death: heart rate variability halved, resting and nocturnal heart rate rose, deep sleep and 6-minute walk distance fell. These coincided with a fatigue complaint and a murmur prompting echocardiography, which revealed severe left ventricular dilation with preserved ejection fraction (approximately 60%), severe mitral regurgitation, moderate aortic regurgitation, and trace tricuspid regurgitation, consistent with advanced structural heart disease.
The key signal was not any single abnormal value but a coordinated, sustained step-change from the patient's own baseline that preceded imaging. Data of this kind could complement the episodic measurements cardiovascular care now relies on, informing both when to re-evaluate patients with known heart disease and how wearable heart-rate kinetics might guide their exercise.
Embedding continuous digital physiology monitoring into traditional cardiology has the potential to aid clinicians in timely evaluation and intervention.
PMID:
42788912
Bibliographic data and abstract were imported from PubMed on 25 Sep 2026.
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