Postoperative outcomes and health care utilization after gastrostomy in children with autism spectrum disorder and developmental delay.

Authors

Blake Hardin, Stephanie Papillon, Claire Wunker, Briana Mezuk, Samir Gadepalli

Published in

Surgery. Pages 110605. Sep 03, 2026. Epub Sep 03, 2026.

Abstract

Gastrostomy tube placement is commonly performed in children with autism spectrum disorder, yet it remains unclear whether autism spectrum disorder is independently associated with postoperative outcomes. We compared short-term outcomes after primary gastrostomy tube placement by autism spectrum disorder and developmental delay status.
Children (<17 years) undergoing laparoscopic gastrostomy tube placement were identified from the American College of Surgeons National Surgical Quality Improvement Program Pediatric (2019-2024). Patient selection was limited to a single institution (n = 386). Autism spectrum disorder status (confirmed [F84.0] or suspected [R68.89]) solicited from individual medical records was linked to National Surgical Quality Improvement Program-Pediatric data. Primary outcomes were postoperative length of stay and a composite 30-day complication outcome. The relationship between autism spectrum disorder and postoperative outcomes was assessed using multivariable regression, accounting for age, sex, developmental delay, and preoperative nutritional support.
Patients with autism spectrum disorder (n = 82) were older (4.9 vs 1.3 years, P < .001) and more likely to have developmental delay (72% vs 41%, P < .001) than those without. Autism spectrum disorder was not associated with longer length of stay (adjusted geometric means ratio, 0.80; P = .27) or postoperative complications (adjusted odds ratio, 0.98; P = .97). Developmental delay similarly was not associated with longer length of stay (adjusted geometric means ratio, 0.52; P < .001), although it was independently associated with short-term postoperative complications (adjusted odds ratio, 1.94; P < .05). Nutritional support was independently associated with longer length of stay (adjusted geometric means ratio, 1.68; P < .01) and higher odds of complications (adjusted odds ratio, 2.36; P = .02).
Autism spectrum disorder is not associated with postoperative length of stay or complications after gastrostomy tube placement. Preoperative nutritional support is strongly associated with postoperative outcomes, suggesting these are driven by overall medical complexity rather than autism spectrum disorder diagnosis.

PMID:
42791101
Bibliographic data and abstract were imported from PubMed on 26 Sep 2026.

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