Pediatric Arboviral Infections in Europe: Epidemiology, Clinical Features, Diagnosis and Prevention.

Authors

Giulia Sturniolo, Silvia Garattini, Denis Doni, Marco Zacchello, Diletta Zanetti, Sofia Galzignato, Andrea Lo Vecchio, Vincenzo Baldo, Daniele Donà

Published in

Viruses. Volume 18. Issue 9. Sep 03, 2026. Epub Sep 03, 2026.

Abstract

Arboviral infections, including West Nile virus (WNV), dengue virus (DENV), chikungunya virus (CHIKV), Zika virus (ZIKV), and, to a lesser extent, Oropouche virus (OROV), pose a heterogeneous and evolving challenge for pediatric health in Europe. The increasing presence of competent vectors and international travel has resulted in both imported infections and, for selected arboviruses, documented autochthonous transmission events. Although pediatric cases are often underrecognized, children may develop severe manifestations, including neuroinvasive disease and congenital infection. Available data on pediatric arboviral infections in Europe remain limited and fragmented, complicating accurate assessment of disease burden and clinical risk. This review summarizes current evidence on the epidemiology, clinical presentation, diagnostic challenges, and prevention of selected arboviral infections in children within the European context, highlighting persistent gaps in pediatric-specific data and implications for preparedness and public health.

PMID:
42797801
Bibliographic data and abstract were imported from PubMed on 26 Sep 2026.

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