[Pathogenic mechanisms and advances in the diagnosis and treatment of co-occurring psychiatric and psychological symptoms in patients with liver cirrhosis].

Authors

H Gong, Y R Li, F N Zhang, T T Zhao, M Huang, C C Liu, N He

Published in

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology. Volume 34. Issue 9. Pages 930-937. Sep 20, 2026.

Abstract

Patients with liver cirrhosis commonly have psychiatric and psychological symptoms, particularly depression, which substantially impairs quality of life and may increase all-cause mortality. However, the pathogenic mechanisms of co-occurring psychiatric and psychological symptoms in cirrhosis remain unclear and may involve multiple factors, including neurobiological alterations, liver dysfunction, primary liver disease, and treatment-related factors. Psychiatric and psychological symptoms can be assessed using diverse scales and managed with pharmacological and non-pharmacological interventions in patients with cirrhosis. This review summarizes the epidemiology, potential pathogenic mechanisms, diagnostic criteria, treatment, and intervention strategies for co-occurring psychiatric and psychological symptoms in patients with cirrhosis, with the aim of providing references for clinical practice.

PMID:
42802131
Bibliographic data and abstract were imported from PubMed on 28 Sep 2026.

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