A method of resin processing and analysis for ovine bone-tendon-implant complex.

Authors

C Broomfield, B Gadomski, D von Stade

Published in

Journal of histotechnology. Pages 1-6. Sep 28, 2026. Epub Sep 28, 2026.

Abstract

Sheep are an accepted model for translational orthopaedic research and histological analysis is a main outcome for many of the studies. Standard paraffin techniques are not appropriate when the tissue has an implant, suture, or other structure that is not supported by paraffin. Resin histology is a technique that supports the implant and permits analysis of the implant/tissue interface. Methyl methacrylate is a common resin choice and has been well documented, but there is a lack of information concerning processing techniques on ovine bone-tendon-implant complexes. Ovine bone-tendon-implant are large (2 cm × 5 cm × 0.4 cm) and have dense fibrous tissue, making them difficult to process and section. This technical note describes a method of grossing, processing, and staining, that produces high‑quality ground slides that allow the pathologist to interpret what is happening at the cellular level.

PMID:
42804338
Bibliographic data and abstract were imported from PubMed on 29 Sep 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.