Authors
Moustapha Agossou, Astrid Monfort-Brafine, Cédric Fagour, Berenice Awanou, Salvatore Metanmo, Marie-Elodie Jean-Charles-Catan, Océane L'heveder, Jocelyn Inamo, Marion Duféal, Mathilde Provost, Nelly Ahouansou, Mathilde Andreu, Jean-Michel Arnal, Chantal Raherison-Semjen, Moustapha Dramé
Published in
BMJ open respiratory research. Volume 13. Issue 1. Sep 28, 2026. Epub Sep 28, 2026.
Abstract
Obesity hypoventilation syndrome (OHS) is a respiratory complication of obesity. Mortality from OHS is non-negligible. Risk factors for OHS-related mortality are not well established and vary in the literature. This study aimed to assess mortality from OHS in patients in Martinique and to identify risk factors for death.
We performed a single-centre, observational study from 1 January 2019 to 31 December 2024, including patients with OHS.
Among 167 included patients, 44 (26.4%) died as of 31 December 2024. 5-year mortality was 12.6%.In multivariable Cox regression, independent predictors of mortality were: OHS diagnosed during acute respiratory failure (HR 6.60, 95% CI 1.50 to 29.10), irregular follow-up (HR 5, 95% CI 1.82 to 14.29), left heart disease (HR 3.63, 95% CI 1.51 to 8.70), lower haematocrit (HR 1.12 per percentage point, 95% CI 1.03 to 1.22) and older age at diagnosis (HR 1.04 per year, 95% CI 1.01 to 1.08).
Mortality among patients with OHS in Martinique remains high. Strategies to improve early diagnosis, cardiovascular risk management and long-term follow-up are essential to improving outcomes in this high-risk population.
PMID:
42805766
Bibliographic data and abstract were imported from PubMed on 29 Sep 2026.
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