Study of a Frugal Design Picosecond Laser System for Laser-Assisted Corneal Surgery.

Authors

Maxime Quirke, Anaïs Langlois, Théo Guilberteau, Pierre Balage, Thomas Hemery, Valentine Saunier, Florent Deloison, Inka Manek-Hönninger, David Touboul, John Lopez

Published in

Journal of biophotonics. Volume 19. Issue 10. Pages e70356.

Abstract

Femtosecond lasers have long been the gold standard for corneal laser-assisted surgery, but their high cost limits widespread use. This study challenges their supremacy by investigating a cost-effective alternative: a frugal all-fiber picosecond laser source. We first conduct a pump-probe experiment to characterize cavitation bubbles in water based on the laser pulse's temporal profile. Picosecond pulses concentrate energy in a confined volume near the focal point, allowing for more precise material interaction than femtosecond pulses. A distortion in the temporal profile, often seen as a flaw, paradoxically further reduces cavitation bubble size. These findings are then applied to ex vivo porcine cornea cutting tests. Results show that 1.5 ps pulses with a distorted profile create sharp, consistent cuts. This study reveals that a cost-effective picosecond laser can rival femtosecond lasers in precision, paving the way for more accessible corneal laser-assisted surgery.

PMID:
42805780
Bibliographic data and abstract were imported from PubMed on 29 Sep 2026.

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