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Risk factors of post-COVID-19 symptoms, a cross-sectional study in patients with asthma and chronic obstructive lung disease.

Created on 29 Sep 2026

Authors

Agnes Andreason, Björn Ställberg, Karin Lisspers, Anna Nager, Hanna Sandelowsky, Josefin Sundh, Gabriella Eliason, Scott Montgomery, Christer Janson, Marta A Kisiel

Published in

NPJ primary care respiratory medicine. Volume 36. Issue 1. Sep 29, 2026. Epub Sep 29, 2026.

Abstract

Post-COVID-19 symptoms are common following COVID-19, but risk factors of persistent symptoms in patients with asthma and chronic obstructive lung disease (COPD) remain unclear. We aimed to assess the frequency and risk factors of post-COVID-19 symptoms in patients with asthma and COPD. In this cross-sectional study, we used data from the Swedish PRAXIS study collected in 2022. The cohort included randomly selected adult patients with a diagnosis of asthma or COPD in medical records from central Sweden's primary and secondary care. Participants completed a comprehensive questionnaire, and their responses were analysed. We used logistic regression and adjusted for age and lung disease diagnoses. Among 494 patients with confirmed COVID-19, 59% (289/494) reported post-COVID-19 symptoms. Risk factors for post-COVID-19 symptoms included severe acute infection (adjusted odds ratio aOR: 8.91, 95% confidence interval [CI]: 3.49-22.8), higher age (aOR:1.25, 95% CI: 1.09-1.45), female sex (aOR: 1.52, 95% CI: 1.04-2.21), and obesity [BMI ≥ 30] (aOR: 2.24, 95% CI: 1.44-3.47)). Anxiety/depression (aOR:1.79, 95% CI: 1.13-2.80) and chronic pain (aOR: 3.61, 95% CI: 1.95-6.69) were also significant risk factors. Patients with asthma or COPD had a high prevalence of post-COVID-19 symptoms compared to other studies. Several demographic and clinical factors were associated with post-COVID-19 symptoms, which could help identify patients at increased risk.

PMID:
42805994
Bibliographic data and abstract were imported from PubMed on 29 Sep 2026.

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