Retrospective analysis of indications and outcomes of trabecular micro-bypass stent implantation in Indian eyes.

Authors

Amit Pandey, Harsh Kumar, Abhishek Kathuria, Sagarika Patyal, Swati Singh, Bhavini Pandey

Published in

Indian journal of ophthalmology. Volume 74. Issue 10. Pages 1473-1477. Oct 01, 2026. Epub Sep 29, 2026.

Abstract

To analyze the patient characteristics, initial outcomes, and complications associated with iStent implantation in Indian eyes.
This retrospective case series comprised subjects who underwent iStent, iStent inject, or iStent inject W implantation as a standalone procedure or combined with phacoemulsification with at least 12 months follow-up. The main outcome measures were change in intraocular pressure (IOP) and number of anti-glaucoma medication (AGM), post op complications, and resurgery rates at the final follow-up.
A total of 56 eyes of 46 patients were included. Twenty-six eyes received iStent, and 30 eyes received either iStent inject or iStent inject W. Mean IOP reduced by 25.5%, and the mean number of AGM decreased by 75.8% at final follow-up ( P < 0.005). The overall success rate was achieved in 51 eyes (85%). When compared to standalone iStent, combined phacoemulsification with iStent delivered greater reduction in AGM ( P = 0.004). Compared to iStent, eyes with iStent inject and inject W had better IOP reduction ( P = 0.03), lesser AGM ( P < 0.005), and a lesser number of surgical failures ( P = 0.045). Three months after iStent inject implantation, trabeculectomy was performed in one eye with secondary glaucoma. Postoperative IOP rise due to steroid response was observed in 20 eyes (35.7%).
iStent implantation in Indian eyes demonstrated promising outcomes in reducing both intraocular pressure and anti-glaucoma medication burden. While combined procedures exhibited superior efficacy in reducing IOP and AGM, postoperative complications such as steroid-induced IOP rise were observed, emphasizing the importance of careful monitoring and management in optimizing surgical outcomes.

PMID:
42809253
Bibliographic data and abstract were imported from PubMed on 30 Sep 2026.

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