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Life-threatening hepatic complications in children with ADA-SCID.

Created on 30 Sep 2026

Authors

Ridhima Aggarwal, Alison Mansfield, Jinhua Xu-Bayford, Claire Booth, Konstantinos Vazouras

Published in

Journal of human immunity. Volume 2. Issue 6. Nov 02, 2026. Epub Sep 30, 2026.

Abstract

We describe two cases of ADA-SCID complicated by hepatoblastoma and infantile hepatic hemangiomatosis. We highlight the multidisciplinary management of these severe liver manifestations and the modifications required to deliver definitive corrective therapy, including gene therapy and hematopoietic stem cell transplantation.

PMID:
42814027
Bibliographic data and abstract were imported from PubMed on 30 Sep 2026.

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