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Transcatheter Tricuspid Valve Replacement in High-Risk Elderly Patients: Procedural Feasibility, Complexity, and Delayed Conduction Disturbances.

Created on 30 Sep 2026

Authors

Lucia Trabucchi, Sergio Torralbas Fitz, Rodolfo Arce, Maria I Ardid, Abraham Abdemur, Nish Patel, Ramon Quesada

Published in

JACC. Case reports. Pages 110532. Sep 30, 2026. Epub Sep 30, 2026.

Abstract

Severe tricuspid regurgitation (TR) is associated with substantial morbidity and mortality and remains undertreated in elderly patients with prohibitive surgical risk. Transcatheter tricuspid valve replacement (TTVR) has emerged as a therapeutic option for anatomies unsuitable for transcatheter edge-to-edge repair.
We report 2 elderly high-risk patients with torrential symptomatic TR who underwent orthotopic TTVR using transfemoral venous access. The first patient, a 94-year-old woman with prior mitral annuloplasty and a transvalvular pacemaker lead, underwent successful TTVR with complete elimination of TR and rapid symptomatic improvement. The second patient, an 84-year-old man with severe leaflet tethering and complex anatomy, underwent successful valve implantation but subsequently developed delayed complete atrioventricular block requiring leadless pacemaker implantation.
These cases demonstrate the feasibility of TTVR in elderly patients with complex anatomy and highlight delayed conduction disturbances as a clinically important complication requiring extended rhythm surveillance.
TTVR is feasible and effective in selected elderly high-risk patients with severe TR and challenging anatomy. Delayed conduction abnormalities may occur several days after implantation and warrant structured rhythm monitoring.

PMID:
42814061
Bibliographic data and abstract were imported from PubMed on 30 Sep 2026.

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