Comment on: "Evaluation of adverse events following endoscopic peroral myotomy (POEM) for achalasia - Implications for feasibility of same-day discharge".

Authors

Muhammad Rehman, Ali Akbar Shahid

Published in

Revista espanola de enfermedades digestivas. Sep 30, 2026. Epub Sep 30, 2026.

Abstract

Calm et al. retrospectively evaluated adverse events (AE) in 76 patients undergoing peroral endoscopic myotomy (POEM) for achalasia and proposed that 87-90% could be candidates for same-day discharge (SDD). We highlight two methodological concerns: the wide confidence interval (95% CI 3.06-1219.86) around the sole independent predictor of grade ≥II AE, based on only 4 events, and the retrospective nature of the SDD eligibility estimate, since all patients in the cohort were actually admitted overnight. We also note that tolerance of oral analgesia, a criterion used in existing SDD protocols, could not be assessed in this study. We suggest that prospective validation incorporating this criterion is needed before the reported eligibility rate is applied to routine practice.

PMID:
42813906
Bibliographic data and abstract were imported from PubMed on 30 Sep 2026.

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