Specific basal ganglia, amygdala, and cortical neurons are associated with borderline personality disorder (BPD).

Authors

Hazal Senturk, Hadar Segal-Gavish, Jason Tucciarone, Laramie Duncan

Published in

bioRxiv : the preprint server for biology. Sep 09, 2026. Epub Sep 09, 2026.

Abstract

Borderline personality disorder (BPD) is clinically significant and poorly understood biologically. We tested which human brain cell types preferentially use genes associated with BPD, implicating two major types of neurons: LAMP5 interneurons and D2 medium spiny neurons. These interrogable cell types provide new avenues for investigating the neurobiology of BPD.

PMID:
42818653
Bibliographic data and abstract were imported from PubMed on 01 Oct 2026.

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