Primary Intraosseous Mucoepidermoid Carcinoma of the Mandible: A Report of a Rare Case.

Authors

Poornima Chikane, Rasika S Kumavat, Rajiv S Desai, Shivani Bansal, Pankaj M Shirsat

Published in

Cureus. Volume 18. Issue 8. Pages e115525. Epub Aug 31, 2026.

Abstract

Mucoepidermoid carcinoma(MEC) is the most common primary salivary gland neoplasm. The exact origin of intraosseous MEC remains uncertain and debated. Although rare, intraosseous MEC is the most common and well-recognized intraosseous salivary gland neoplasm. Histopathological examination revealed cystic and solid epithelial components comprising mucous, epidermoid, and intermediate cells, with strong intracytoplasmic mucicarmine positivity, supporting a diagnosis of low-grade primary intraosseous MEC. The patient subsequently underwent hemimandibulectomy at a higher oncology center and remained disease-free during the available follow-up period. The diagnosis of intraosseous MEC presents a diagnostic challenge due to its clinical and radiological resemblance to various benign odontogenic cysts and tumors. We present an interesting case of intraosseous MEC in a 23-year-old female patient.

PMID:
42819582
Bibliographic data and abstract were imported from PubMed on 02 Oct 2026.

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