Kinesiopathology, a Framework for Progressive Nature of Neuromusculoskeletal Dysfunctions: Implications for Physical Therapy.

Authors

Maiko Morotani

Published in

Physical therapy research. Volume 29. Issue 2. Pages 79-86. Epub Jun 30, 2026.

Abstract

Kinesiopathology describes how suboptimal movement patterns generate progressive mechanical stress on tissues, contributing to structural changes and the onset of neuromusculoskeletal pain conditions. The purpose of this article is to discuss kinesiopathology as a framework for understanding the progressive nature of neuromusculoskeletal dysfunctions and its implications for physical therapy practice. Empirical evidence from biomechanical and clinical research across multiple conditions supports the relationship between altered movement patterns and musculoskeletal pathology. The nervous system consolidates frequently repeated movement patterns into automatized motor programs that operate below conscious awareness, perpetuating suboptimal tissue loading over time. This supports the reframing of traditionally defined orthopedic conditions as neuromusculoskeletal conditions, in which neuromuscular activation patterns govern movement behavior and influence tissue stress. Five phases of kinesiopathology are proposed, describing the progression from subtle, asymptomatic movement patterns through repetitive tissue loading, structural changes, and symptom development to chronic neuromusculoskeletal dysfunction. This framework highlights the clinical value of the early identification and modification of suboptimal movement patterns. Systematic movement system examination-including observation of alignment, neuromuscular activation patterns, and movement strategies during functional tasks-positions physical therapists to identify and address the movement-related mechanisms underlying neuromusculoskeletal conditions. How a person moves is not incidental to their neuromusculoskeletal health, but is fundamental to it. As movement system experts, the recognition and modification of movement dysfunction in its earliest phases represent both the defining competency and the greatest clinical opportunity of the profession.

PMID:
42819688
Bibliographic data and abstract were imported from PubMed on 02 Oct 2026.

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