Authors
Ruijie Zhang, Li Mei, Melody Liu, Olivia Liong, Leo Liu, Lu Jiang, Qianming Chen, Ajith Polonowita, Guangzhao Guan
Published in
Oral surgery, oral medicine, oral pathology and oral radiology. Jul 07, 2026. Epub Jul 07, 2026.
Abstract
To investigate the proficiency of artificial intelligence (ChatGPT-4 and DeepSeek-v3) in responding to frequently asked questions (FAQs) related to oral lichen planus (OLP).
Twenty-three OLP-related FAQs were adapted from known sources. Responses generated by ChatGPT-4 and DeepSeek-v3 were assessed by expert panels across 5 domains: accuracy, comprehensibility, logic, fairness, and simplicity.
DeepSeek-v3 outperformed ChatGPT-4 in comprehensiveness (4.65 ± 0.37 vs 4.04 ± 0.54; P < .001), logic (4.41 ± 0.32 vs 4.03 ± 0.35; P < .001), and fairness (4.34 ± 0.33 vs 4.03 ± 0.27; P < .001). ChatGPT-4 scored higher in simplicity (4.25 ± 0.31 vs 4.04 ± 0.28; P = .034), while DeepSeek-v3 had a modest advantage in accuracy (4.49 ± 0.38 vs 4.22 ± 0.34; P = .025). DeepSeek-v3 performed better in comprehensiveness and logic for "Causes" and "Symptoms," and in accuracy for "Risk & Complications." ChatGPT-4's simplicity was most evident in "Causes" and "Symptoms." In "Treatment & Management," DeepSeek-v3 excelled in logic and comprehensiveness, while ChatGPT-4 showed greater simplicity and occasional accuracy.
ChatGPT-4 provides concise, accessible information, whereas DeepSeek-v3 offers broader, more detailed responses. Combining both models may improve patient understanding of OLP.
PMID:
42823233
Bibliographic data and abstract were imported from PubMed on 02 Oct 2026.
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