Prevalence of Congenital Cytomegalovirus Infection in a CMV-Endemic Ugandan Population.

Authors

Amy K F Davis, Mary K Prahl, Mikias Ilala, Justine Levan, Pamela M Odorizzi, Mary Muhindo, Abel Kakuru, Stephanie L Gaw, Moses R Kamya, Grant Dorsey, Margaret E Feeney

Published in

Open forum infectious diseases. Volume 13. Issue 10. Pages ofag566. Epub Sep 05, 2026.

Abstract

Congenital cytomegalovirus (cCMV) infection is a leading cause of childhood deafness and disability worldwide. However, less is known about its epidemiology in low-income regions where most women are CMV-seropositive at conception. We found that cCMV is highly prevalent in rural Uganda (3.73%) and is associated with lower gravidity and placental malaria. We additionally report a high transmission intensity in the first years of life, with 97.3% of children acquiring CMV IgG by age 3.

PMID:
42819885
Bibliographic data and abstract were imported from PubMed on 02 Oct 2026.

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