A (Post)translational Opportunity in RAS-Dependent Heme Malignancy.

Authors

Lawrence H Boise

Published in

Blood cancer discovery. Pages OF1-OF3. Oct 02, 2026. Epub Oct 02, 2026.

Abstract

Zhang and colleagues uncover a mechanism of regulation of RAS stability that is active almost exclusively in hematologic (heme) malignancies. This provides new insights into the consequences of a RAS hotspot mutation found in leukemia and myeloma and points to a new therapeutic opportunity in these diseases. See related article by Zhang et al., p. XX.

PMID:
42825592
Bibliographic data and abstract were imported from PubMed on 02 Oct 2026.

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