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Metabolism: A constraint and driver of neurodevelopment.

Created on 02 Oct 2026

Authors

Maheen Siddiqui, Emily J H Jones

Published in

The Behavioral and brain sciences. Volume 49. Pages e478. Oct 02, 2026. Epub Oct 02, 2026.

Abstract

This commentary extends recent accounts of metabolic constraints in cognitive modelling by considering their role in brain development. We argue that shifting energy availability both constrains and drives the emergence of functional specialisation and network organisation. Integrating interactive specialisation, we show how metabolic factors shape competitive and cooperative interactions, and how atypical energy metabolism may contribute to neurodivergent developmental trajectories.

PMID:
42825757
Bibliographic data and abstract were imported from PubMed on 02 Oct 2026.

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