Authors
Mengge Wang, Yuhang Feng, Moru Guo, Zhiyong Wang, Yunhui Liu, Jun Yao, Haibing Yuan, Jing Chen, Yuguo Huang, Renkuan Tang, Jiangwei Yan, Bofeng Zhu, YanHuang Consortium, Haohao Dong, Binwu Ying, Chao Liu, Guanglin He
Published in
Science advances. Volume 12. Issue 40. Pages eaeg8897. Oct 02, 2026. Epub Oct 02, 2026.
Abstract
Human populations across Eurasia have long been connected through the steppe corridor and Silk Road, yet their paternal genetic history remains poorly understood. We integrated large-scale Y-chromosome data, including 1053 previously unreported sequenced genomes, to reconstruct Eurasian spatiotemporal paternal phylogeny. This resource identified 15,810 previously unidentified variants, improving the resolution of Y-chromosome phylogeny and enabling more accurate placement of ancient Eurasians. Paternal lineages in Northwest China changed gradually over time. Bronze Age Xinjiang populations were largely dominated by Xiaohe-related local lineages or western steppe herder lineages, while Iron Age and later populations showed increasing paternal contributions from East Asian farmers, eastern steppe pastoralists, and Southwest/Central Asian farmers. Modern Altaic-speaking populations showed strong paternal continuity with Iron Age ancestry, and northwestern Han displayed a west-to-east gradient of paternal lineages. Four Hui substructures showed differentiated paternal profiles shaped by both migration and cultural assimilation. Overall, the results revealed a complex pattern of population movements shaping paternal ancestry across northwestern East Asia.
PMID:
42826189
Bibliographic data and abstract were imported from PubMed on 03 Oct 2026.
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