Authors
Qian Cheng, Somaye Fatahi, Mohammad Reza Amini, Pejman Rohani, Mohammad Hassan Sohouli
Published in
Diabetes research and clinical practice. Pages 113588. Oct 03, 2026. Epub Oct 03, 2026.
Abstract
Corn-derived dietary fibers have been increasingly recognized for their potential cardiometabolic benefits; however, evidence regarding their effects on cardiometabolic markers remains inconsistent. This systematic review and meta-analysis aimed to evaluate the effects of corn-derived dietary fiber supplementation on cardiometabolic outcomes in adults. A systematic search of original databases was conducted from database inception to May 2026 to identify randomized controlled trials investigating the effects of corn-derived dietary fibers. Weighted mean differences (WMDs) with 95% confidence intervals (CIs) were calculated using a random-effects model. Corn-derived dietary fiber supplementation significantly reduced total cholesterol (TC) (WMD: -7.93 mg/dL; 95% CI: -14.00 to -1.86) and low-density lipoprotein- cholesterol (LDL-C) (WMD: -8.82 mg/dL; 95% CI: -14.31 to -3.33). No significant effects were observed for glycemic control, other lipid profile, anthropometric indices, blood pressure, and C-reactive protein (all P > 0.05). Subgroup analyses showed that the lipid-lowering effects remained generally consistent across intervention durations and fiber dosages. Corn-derived dietary fiber supplementation significantly improves TC and LDL-C concentrations but has no significant effects on other cardiometabolic outcomes. These findings support the potential role of corn-derived dietary fibers as an adjunct nutritional strategy for improving lipid profile and reducing cardiovascular risk.
PMID:
42829185
Bibliographic data and abstract were imported from PubMed on 04 Oct 2026.
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