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Baseline characteristics and practice patterns in geriatric vs. non-geriatric hemodialysis patients: initial results from a Thai nationwide multicenter prospective cohort (Thai-HDcohort).

Created on 05 Oct 2026

Authors

Wanjak Pongsittisak, Jeerath Phannajit, Wonngarm Kittanamongkolchai, Theerasak Tangwonglert, Thawee Chanchairujira, Kraiwiporn Kiattisunthorn, Kornchanok Vareesangthip, Bongkod Surattichaiyakul, Arkom Nongnuch, Surachet Vongsanim, Pantipa Tonsawan, Pornpen Sangthawan, Siribha Changsirikulchai, Phanupong Phutrakool, Peerapat Thanapongsatorn, Pichaya Tantiyavarong, Talerngsak Kanjanabuch, Khajohn Tiranathanagul, Suchai Sritippayawan, Suree Yoowannakul, Vuddhidej Ophascharoensuk, Paweena Susantitaphong

Published in

Renal failure. Volume 48. Issue 1. Pages 2735561. Epub Oct 04, 2026.

Abstract

Older adults represent a rapidly growing segment of the hemodialysis (HD) patient population. However, the specific clinical variations and dialysis management strategies employed for geriatric patients in Thailand remain poorly characterized.
We analyzed baseline data from 839 hemodialysis patients enrolled in the Thai-HDcohort, a prospective multicenter study across 13 clinical sites in Thailand. Patients were stratified into a geriatric group (≥ 65 years of age, n = 412) and a younger control cohort (< 65 years of age, n = 427). Demographics, vascular access modalities, baseline laboratory markers, pharmacotherapy, and dialysis prescriptions were compared between the two groups.
Geriatric patients were more frequently treated in hospital-based facilities (75.0% vs. 67.4%, p = .002). The geriatric group exhibited lower body weight (57.7 vs. 63.0 kg, p < .001) and lower serum albumin (hypoalbuminemia prevalence: 11.6% vs. 5.1%, p = .001). Regarding practice patterns, geriatric patients relied more heavily on tunneled cuffed catheters at enrollment (38.1% vs. 27.7%, p = .005) and were likely to initiate HD using a catheter (41.0% vs. 27.1%, p < .001). Geriatric prescriptions also favored a higher utilization of a 3.0 mmol/L dialysate potassium bath (40.0% vs. 23.7%, p < .001), and a higher dialysate calcium bath of 3.0 mmol/L (19.9% vs. 12.9%, p = .011).
In this cross-sectional study, geriatric hemodialysis patients showed distinct variations in prescriptions and vascular access. Longitudinal follow- up is essential to determine whether these conservative, individualized strategies improve clinical and survival outcomes.

PMID:
42830578
Bibliographic data and abstract were imported from PubMed on 05 Oct 2026.

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