Correlation of size specific dose estimates with organ dose in abdominal spectral computed tomography.

Authors

Tian Qin, Qingting Sun, Yihan Fan, Mengting Wang, Jing Wang, Yankui Chang, Baohui Liang

Published in

Journal of applied clinical medical physics. Volume 27. Issue 10. Pages e70845.

Abstract

In abdominal spectral Computed Tomography (CT), organ dose assessment is important for radiation safety but remains challenging due to the complexity of Monte Carlo (MC) simulations.
This study aimed to compare the correlations of three size-specific dose estimate (SSDE) metrics (including the central slice SSDE_center, the mean of all slices SSDE_mean, and the organ-specific SSDE_organ) with organ doses and to establish a rapid estimation method for organ dose using linear regression in abdominal spectral CT.
Monte Carlo N-Particle (MCNP6) was used to model the General Electric (GE) Revolution CT scanner, including its bowtie filter, radiation source, and simulations of tube voltage switching and the X-ray tube trajectory. Digital Imaging and Communications in Medicine (DICOM) data from 30 patients undergoing abdominal spectral CT with identical scan parameters were processed using 3D Slicer. Radiation-sensitive organs were delineated. Following this, digital models were constructed and subsequently voxelized. All patient external body contours were delineated using ImageJ software. Three SSDE metrics were calculated for all patients. Linear regression analysis was performed to correlate organ doses with the three SSDE metrics and to derive estimation coefficients.
The results indicated that in abdominal spectral CT examinations on a Revolution scanner, SSDE_organ exhibited the strongest correlation with organ dose. The R² values for the liver, stomach, pancreas, spleen, kidneys, spinal cord, and bladder were 0.89, 0.61, 0.81, 0.85, 0.88, 0.94, and 0.68, respectively. The corresponding estimation coefficients derived from SSDE_organ for these organs were 0.42, 0.36, 0.37, 0.41, 0.36, 0.26, and 0.26, respectively. The estimation errors for the conversion coefficient combined with SSDE_organ, relative to the MC simulation results, were 7.34% for the liver, 6.09% for the kidneys, 13.25% for the spleen, 2.97% for the spinal cord, 13.61% for the pancreas, 17.64% for the stomach, and 18.56% for the bladder.
For abdominal spectral CT, SSDE_organ demonstrated the strongest correlation with individual organ doses. These findings enable rapid and accurate estimation of organ dose, providing a basis for personalized radiation dose assessment in clinical practice.

PMID:
42834551
Bibliographic data and abstract were imported from PubMed on 06 Oct 2026.

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