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Neonatal Outcomes in Twin Pregnancies with Birthweight Discordance: A five-year retrospective cohort study.

Created on 06 Oct 2026

Authors

Marjan Mahboubi, Shadya Mohammed Salim Al Saeghi, Hansa Dhar, Dina Mohamed Abd El Fatah, Rowaida Elraih Omran Mensour, Qamariya Khalfan Saud Ambu-Saeidi

Published in

Sultan Qaboos University medical journal. Volume 26. Issue 1. Pages 515-521. Epub Sep 16, 2026.

Abstract

This study aimed to evaluate neonatal outcomes associated with birthweight discordance in twin pregnancies managed at a regional tertiary care centre in Oman.
This five-year retrospective cohort study (2020-2024) was conducted at Nizwa Hospital, Nizwa, Oman, and included twin pregnancies of ≥24 weeks' gestation. Birthweight discordance was defined as ≥20%. Multivariable logistic regression analysis was performed, adjusting for gestational age at delivery, chorionicity, preeclampsia and gestational diabetes mellitus.
A total of 226 twin pregnancies were included, of which 45 (19.9%) had birthweight discordance ≥20%. Discordant pregnancies were delivered at an earlier gestational age than non-discordant pregnancies (34.2 ± 2.9 versus 35.3 ± 2.2 weeks; P = 0.017). NICU admission was more frequent in the discordant group (60.0% versus 31.5%; P <0.001), as was the composite adverse neonatal outcome (62.2% versus 33.1%; P <0.001). Birthweight discordance ≥20% remained independently associated with the composite adverse neonatal outcome (adjusted odds ratio [aOR] = 2.74, 95% CI: 1.21-6.25; P = 0.016), while increasing gestational age at delivery was protective (aOR = 0.47 per additional week, 95% CI: 0.37-0.59; P <0.001).
Birthweight discordance ≥20% was associated with adverse neonatal outcomes in twin pregnancies, with this association largely mediated by prematurity.

PMID:
42836167
Bibliographic data and abstract were imported from PubMed on 06 Oct 2026.

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