Authors
Ricardo Madrigal-Burgaleta, Emilio Alvarez-Cuesta, Knut Brockow, Jean-Christoph Caubet, Lene H Garvey, Antonieta Guzman-Melendez, Marina Labella Alvarez, Lina Mayorga, Paula Vazquez-Revuelta, Ignacio J Ansotegui, Steering committee authors;, Marina Attanasi, Marcelo Vivolo Aun, Joan Bartra, Sevim Bavbek, Maria Pilar Berges-Gimeno, Lorena Bernal-Rubio, Cosmin Boteanu, Lucrecia Bustamante, Carlo Caffarelli, Timothy G Chow, Bryan N Fernandes, Pedro Giavina-Bianchi, David Khan, Semanur Kuyucu, Jose Julio Laguna, Jonathan Lambourne, Lily Li, Susana Marinho, Francesca Mori, Allison E Norton, Valeria Palma Pino, Claudio A S Parisi, Hae-Sim Park, Elizabeth Powell, Eva Rebelo Gomes, Antonino Romano, Marek Sanak, Rik Schrijvers, Emilio Solano-Solares, Luciana Kase Tanno, Rocco Luigi Valluzzi, Rosalaura Villarreal-Gonzalez, Timothy J Watts, Andrew A White, Masao Yamaguchi, Review panel authors
Published in
The World Allergy Organization journal. Volume 19. Issue 10. Pages 101467. Epub Sep 26, 2026.
Abstract
Hypersensitivity reactions to intravenous therapies-including antibiotics, chemotherapeutics, biologics, anesthesia agents, and contrast media-pose significant challenges in acute care settings. These reactions often occur outside the purview of allergy specialists, leading to delays in recognition, suboptimal management, and inconsistent documentation. This article underscores the imperative for proactive, multidisciplinary collaboration to enhance patient safety and treatment continuity. We examine the spectrum of intravenous reactions, including anaphylaxis, highlighting the pivotal role of allergists in both acute intervention and long-term care planning. Emphasis is placed on the development of standardized protocols, the establishment of inpatient allergy consult teams, and the implementation of penicillin allergy delabeling strategies. Supplemental materials provide real-world examples from leading institutions that have successfully integrated multidisciplinary approaches, demonstrating improved outcomes through coordinated care. By proactively engaging in the creation of safety protocols, referral pathways, and joint models of care, allergy specialists can contribute significantly to safer patient environments, even before reactions occur, ensuring timely diagnosis, effective management, and optimal outcomes.
PMID:
42835668
Bibliographic data and abstract were imported from PubMed on 06 Oct 2026.
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