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Three-year follow-up of individualized respiratory rehabilitation therapy for post-infectious bronchiolitis obliterans: a pediatric case report.

Created on 07 Oct 2026

Authors

Li Peng, Zhongkai Kuai, Tuhong Yang, Xia Qin, Yan He, Xiaoling Zi, Ling Li, Dan Liu, Yao Liu, Yijun Cheng, Lili Zhong

Published in

Journal of pediatric nursing. Sep 22, 2026. Epub Sep 22, 2026.

Abstract

Bronchiolitis obliterans (BO), a common chronic obstructive pulmonary disease following severe lung infection, imposes a significant burden on patient health. This study aimed to explore the potential application of individualized respiratory rehabilitation programs for pediatric patients.
This study reports a case of a 13-year-old boy with BO following severe influenza virus infection. A comprehensive nurse-led intervention combining individualized respiratory rehabilitation, remote management, patient education, and self-management with routine care was implemented, with over three years of follow-up. During the hospitalization phase, specialist nurses supervised and guided the patient in completing daily rehabilitation training and symptom monitoring. After discharge, the nurses served as the central coordinators of care, achieving real-time data collection, immediate physician-patient interaction, and dynamic regimen optimization through the remote management platform.
Follow-up results showed significant improvements in lung function and moderate obstructive ventilatory dysfunction. Specifically, FEV1/FVC increased from 84.4% to 92.4%, 6-min walk distance recovered from 85% to 110% of the predicted value, maximum inspiratory pressure (MIP) increased from 65 cmH2O to 82.95 cmH2O, and maximum expiratory pressure (MEP) rose from 75 cmH2O to 87.7 cmH2O. Simultaneously, Borg, GAD-7, and PHQ-9 scores all decreased. Imaging follow-up showed no significant progression of bilateral lung lesions.
This case report demonstrates that this nurse-led comprehensive management model was associated with improvements in lung function, exercise tolerance, respiratory muscle strength, and mental health in a pediatric BO patient, providing promising preliminary evidence and an innovative paradigm for multidisciplinary management of pediatric BO.

PMID:
42838806
Bibliographic data and abstract were imported from PubMed on 07 Oct 2026.

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