Authors
Weiying Zhong, Xiamin Zhu, Fang Tang, Lan Xu
Published in
Frontiers in nutrition. Volume 13. Pages 1939731. Epub Sep 22, 2026.
Abstract
Malnutrition is common among patients with hematologic malignancies, but there are few clinical studies on disease-specific nutritional characteristics and the appropriateness of nutritional support.
This cross-sectional study included 633 hospitalized patients with hematologic malignancies. Nutritional risk was assessed using the NRS-2002, malnutrition was diagnosed according to GLIM criteria, and the appropriateness of nutritional support was evaluated.
54.0% of patients were at nutritional risk, and 39.0% were diagnosed with malnutrition. Significant heterogeneity was observed across different disease subtypes, with multiple myeloma having the highest prevalence of nutritional risk (66.3%) and leukemia having the highest prevalence of malnutrition (44.9%). Female gender, diabetes, hypertension, elevated C-reactive protein, infection, and low serum albumin levels were independent risk factors associated with malnutrition. Only 15.6% of patients received nutritional support; fewer than one-third of malnourished patients received nutritional intervention, while 7.0% of well-nourished patients received nutritional support without clear indications.
There is significant heterogeneity in the nutritional status of hospitalized patients with hematologic malignancies, and a marked mismatch exists between nutritional needs and nutritional support. Disease-specific nutritional management based on the GLIM assessment may improve the appropriateness of nutritional support and optimize clinical outcomes.
PMID:
42839928
Bibliographic data and abstract were imported from PubMed on 07 Oct 2026.
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