Synthesis of a C-14 Labeled Heme.

Authors

Cecilia Ericsson, Jonas Bergare, Charles S Elmore

Published in

Journal of labelled compounds & radiopharmaceuticals. Volume 69. Issue 12. Pages e70042.

Abstract

In support of a discovery biology project, a C-14 labeled heme was required. The C-14 label was located in the carbon connecting the A and B ring with a propionic acid side chain on both the C and D ring and alkyl substitution on the remaining positions of the pyrrole rings of the heme. The synthesis was achieved in 7 radiochemical steps and 11% radiochemical yield from ¹⁴C-formaldehyde. A stability study showed that the compound decayed at about 0.5%/month in a linear fashion.

PMID:
42839786
Bibliographic data and abstract were imported from PubMed on 07 Oct 2026.

Read full publication at:
Please sign in to see all details.

Stats

1-terrible, 9-excellent. How would you rate this publication? Sign in in to submit your rating.

Post a comment

You need to be signed in to post comments. You can sign in here.

Comments

There are no comments yet.