Authors
Marieke de Swart, Dijana Spasenoska, Eli Harriss, Vincent Cheng, Katrin Probyn, Gemma Villanueva, Thomas Mendy, Musawenkosi Ndlovu, Brian Buckley, Daniela Toale, Nicholas Henschke, Duduzile Ndwandwe, Alice Norton, Louise Sigfrid
Published in
Wellcome open research. Volume 10. Pages 668. Epub May 25, 2026.
Abstract
Systematic reviews require time and resources to conduct that might not be available in a rapidly developing context such as during new and (re-) emerging infectious disease outbreaks. As part of the Pandemic-PACT program at the Pandemic Sciences Institute at the University of Oxford we have, in collaboration with Cochrane Response and Cochrane South Africa, developed a "living" Rapid Research Needs Appraisal (RRNA) methodology. The aim is to develop a protocol for rapidly and robustly identify key evidence gaps across pre-defined research domains to inform research prioritisation and coordination in preparedness time and during outbreaks. The RRNA utilises modified systematic review methods, a global relay of reviewers, and systematic review software. The objective is to strengthen capability for carrying out RRNAs, and establish a baseline evidence platform for priority infectious diseases that can be readily updated as new evidence emerges, utilising an adaptable "living" RRNA protocol. This data will be of relevance to funders, researchers, clinical and public health stakeholders involved in management of infectious diseases of epidemic and pandemic potential.
PMID:
42845321
Bibliographic data and abstract were imported from PubMed on 08 Oct 2026.
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