68Ga-DOTATATE PET/CT Detection of Hypertrophic Osteoarthropathy in a Pediatric Patient With Neuroblastoma Following Anti-GD2 Immunotherapy.

Authors

Siqi Li, Xiaoya Wang, Keyu Zhang, Wei Wang, Jigang Yang

Published in

Clinical nuclear medicine. Volume 51. Issue 11. Pages 1030-1032. Nov 01, 2026. Epub Oct 08, 2026.

Abstract

A 5-year-old boy with high-risk neuroblastoma underwent 68Ga-DOTATATE PET/CT as part of a clinical trial to assess treatment response after anti-GD2 immunotherapy. The scan showed symmetric increased uptake in bilateral femora and tibiae with periostosis. 18F-MFBG PET/CT revealed no abnormal uptake, and no metastasis was found. The diagnosis was hypertrophic osteoarthropathy. This case demonstrates that hypertrophic osteoarthropathy can occur as a rare complication after anti-GD2 therapy and can be detected by 68Ga-DOTATATE PET/CT.

PMID:
42853990
Bibliographic data and abstract were imported from PubMed on 10 Oct 2026.

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